Title: Full Stack Development for Structural Bioinformatics
Presenter: Woonghee Lee
National Magnetic Resonance Facility At Madison (NMRFAM), and Biochemistry Department
University of Wisconsin-Madison, Madison, WI 53706 USA
While the origin of most biological phenomena is genetic information, transcribed RNA molecules and translated proteins are the main actors. Atomic structures, dynamics, ligand interactions and catalysis of biomolecules are key components of understanding biological processes. Nuclear magnetic resonance (NMR) spectroscopy is one of the major physical techniques used for studying protein structure, dynamics and function. However, it is not used routinely by scientists because the high level of expertise required for data collection and data analysis. My research has focused on creating a seamless, interactive environment to lower the barrier for practical research. In this talk, I will present an automated and integrated software platform for efficient and easy-to-use protein structure and function studies using NMR and other sources of data describing full stack development encompassing relational database management system (RDBMS),
Bayesian inference, sequence alignment algorithms, graphical user interfaces (GUIs), web development, etc.
Organizer: Trish Artis